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And what GLP-1 seems to do whether its [being used by] the person who cant wait to finish the cheesecake, or the person whos smoking and having cannabinoids, or [consuming] opioids or alcohol is take down the level of pleasure that we get

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Since AOMs are indicated in combination with lifestyle interventions, all participants received dietary and physical activity counseling, aiming to achieve a 500-kcal deficit per day and 150 minutes of physical activity per week