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Mesenchymal stem cell transplantation exerts a beneficial role also in the EAE mice, the animal MS model, promoting a functional recovery ( 2+ levels by the modulation of calbindin expression, which is associated with calcium homeostasis and plays a role in the protection of dopaminergic neurons in the pathogenesis of PD (Liu et al., 2014)
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Therefore, vitamin B12 has a safe profile
Using mass spectrometry (MS) approach, we then showed that the resulting NCs bind carbonylated proteins through the formation of an oxime bond between the aminooxy-containing thiolated ligand on the NC and the carbonylated amino acid on the protein
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