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If excess FAs are deposited in ectopic tissues, this could lead to lipotoxic effects of FAs

[9] The function of carnitine as a transmitter of fatty acids through the inner membrane of the mitochondria for use in the process of oxidation, facilitating the reabsorption of acetyl CoA, increasing the production of acetylcholine, increasing the production of phospholipids in cell membrane, and preventing the death of neural cells is some of the proposed mechanisms

This variability adds an additional layer of uncertainty when considering berberine use during breastfeeding, as the actual content and quality of products can differ significantly between manufacturers

In this context, metabolic compounds, such as carnitines, with positive effects on mitochondrial activity and free radical scavenging, can contribute to mitigate the effects of PCOS