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Kataya AR, Reumann S

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The emergence of -synuclein pathology follows microglial activation, suggesting -synucleins pivotal role in PD progression, albeit not as an initiator

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In addition, acylcarnitine accelerates the degradation of the PD1 protein by promoting the acetylation of the E3 ubiquitin ligase FBXO38, revealing not only the mediating role of acylcarnitine in mitochondrial communication between platelets and B cells but also its epigenetic regulatory role in regulating mitochondrial function and PD1 degradation [43]

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