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All positively stained cells were counted and the % Nissl positive neuron was calculated by dividing the number of positive neurons by the total number of neurons in each cell [1]

Indeed, we observed an increase in xanthine dehydrogenase (XDH) mRNA expression, the enzyme responsible for transforming purine bases into uric acid 50 (Fig

The mechanisms driving these effects are multifaceted, involving the suppression of neuroinflammation via the TLR4/NF-B pathway and restoration of brain energy metabolism through the activation of the AMPK and SIRT1/GLUT4 signaling cascades (Wang et al., 2023

For people with type 2 diabetes, GLP-1 drugs can help in two key ways: they lower blood sugar levels and support weight loss