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GLP-1 receptor activation inhibits the activation of hepatic Kupffer cells and infiltrating macrophages, leading to decreased production of pro-inflammatory cytokines such as TNF- and IL-1, thereby attenuating hepatic inflammation (44)
However, as with any peptide, individual reactions can vary, and its advised to consult with a healthcare professional before use
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However, in practice, investigators could only introduce a small amount of stratification and could not balance all important variables simultaneously (23)
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