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The cellular complexity-related features of apoptosis: involvement of organelles Apoptosis is a caspase-dependent RCD which was first described in 1972 based on a characteristic cellular morphology such as cell shrinkage, nuclear condensation, formation of apoptotic bodies, etc [71, 72]

These materials can break or be easily punctured by a needle

CD8 + T cells of the knockout mice were intrinsically defective in balancing homeostasis in the peripheral environment, implicating GPX4 is required for T cell-regulated immune responses (Matsushita et al., 2015)