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GLP-1 agonist semaglutide reduced diabetes risk (HbA1c) and weight (20 lb) in new RCT of people with #schizophrenia, prediabetes, and obesity: Evidence grade: High (10/10) How to use GLP-1s: #psychiatry #pmhnp There is growing evidence that not only are GLP-1 RAs highly effective in reversing and preventing psychotropic-induced weight gain, but they also might have a direct role in the treatment of several neuropsychiatric disorders, due to a series of properties summarized in this figure (McIntyre RS et al

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Berchtold L, Crowe LA, Friedli I et al (2020) Diffusion magnetic resonance imaging detects an increase in interstitial fibrosis earlier than the decline of renal function

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