glp-1 data Receptor Agonist Market Report 2026 GLP-1 RA prescription trends: January

First, approximately 1 in 4 patients had discontinued treatment at 1 year after treatment initiation, and almost half had discontinued at 3 years, with these findings being largely similar for GLP-1 receptor agonists and SGLT2 inhibitors

The Bottom Line (Plain English) Weeks 12: appetite changes, little scale movement Weeks 36: weight loss often begins Months 36: meaningful, sustained loss for many Semaglutide: slower start, steady progress Tirzepatide: faster early loss for some, same long-term rules apply GLP-1 rewards patience not urgency

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