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Copper is a co-factor for lysyl oxidase, the enzyme that cross-links newly synthesised collagen and elastin fibres into load-bearing structures

On the contrary, the defect sites injected with GSH-high hES-MSCs showed the greatest regenerative effects on articular cartilage, with dense Safranin-O staining, indicating that more hyaline cartilage and proteoglycans were generated on the defects (Fig

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