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The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions

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6 Cellular senescence and UV-induced inflammation result in greater regenerative signaling requirements and attenuated peroxisome proliferator-activated receptor expression, resulting in fewer differentiated, mature adipocytes

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As more data comes in, I become more convinced that we may look back on these drugs as the greatest medical breakthrough of the 21st century. 2

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