The phase two trial, which had 40 patients, was conducted in Croatia, and some people question the validity of the study due to its location, but the groups conducting the trials seem to be doing robust, randomized, control, double-blind, placebo-control trials 2m6s
10.1097/MOH.0000000000000418 2 AbedM.ArtuncF.AlzoubiK.HonischS.BaumannD.FllerM.et al (2014)
While tirzepatide does not directly target these pathways, the metabolic improvements and weight reduction it facilitates may indirectly support healthier reproductive hormone profiles
Furthermore, as for melanocytes, we treated the cells with Compound C and the results proved that AMPK inactivation negatively influences autophagy process also in vitiligo fibroblasts, at 24 h of treatment (Fig