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Each sample was thereafter incubated with 10 l of acetonitrile and stored at 20 C before analysis was performed on a Beckman HPLC instrument operated with System Gold coupled to diode array UVVIS detector module 168
NAC, in particular, has been shown to increase glutathione levels in the liver and other tissues (1)
Controlling the role of BPC 157 likely involves its particular interaction with the major systems involved in wound healing, such as the NO-system (counteracted harmful events, arising from either NO-blockade or NOS-substrate application) (Sikiric et al., 2014) and the prostaglandins system (i.e., large extent of the counteracted NSAIDs toxicity (Sikiric et al., 2013) as well as counteracted developing and already formed adjuvant arthritis in rats (Sikiric et al., 1997c))
When such an interaction is disrupted, the healing is delayed and may result in excessive inflammation and scarring
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