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Cao Q, Kazi H, Merchant AM, Jawed AE

A significant subsequent advance was the construction of a de novo physical map (~340 Mb) using BioNano Genomics, which enabled a hybrid assembly that nearly doubled the N50 to 697 kb and greatly improved genome continuity (Clouse et al., 2016)

At 1 mg, the GIP receptor is roughly 48% engaged and the liver is already burning fat (51% reduction in the MASLD substudy)

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