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324 In an eight-week, randomized, open-label, controlled trial of patients with varied subtypes of IBS, treatment with colestipol significantly improved IBS symptoms

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Levels of Glp1r mRNA were not different in the kidney or renal artery of Glp1r Tie2+/+ versus Glp1r Tie2/ mice but were markedly reduced in the lung of Glp1r Tie2/ mice, a tissue enriched in ECs (Figure 3, DF)