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105,393,394,395 Conclusions In summary, toxic encephalopathies are primary astrocytopathies, in which toxic substances are accumulated by and damage astrocytes, with neuronal loss being secondary to astroglial homoeostatic failure

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While long-term, high-dose use of these may eventually support levels, it is often considered an inefficient route

Viscosity is a critical quality attribute because it directly affects pump performance (higher viscosity requires more force to actuate), valve function, and droplet size distribution (more viscous formulations tend to produce larger droplets with reduced aerosol fineness)