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Antiepileptic Drugs (e.g., Phenytoin, Phenobarbital) Effect: May alter Vitamin B levels and reduce therapeutic effectiveness

He was juggling an injury to his back, not being able to exercise as much due to back pain, not eating the healthiest diet due to his work schedule, and certain medications he was on were triggers for his weight gain

For example, the combination of the cancer drug Dasatinib and the natural compound Quercetin was shown to induce apoptosis in senescent cells in a variety of contexts in vitro and in vivo 1,4

The study confirmed that FOXO4-DRI disrupts FOXO4-p53 binding in endothelial cells, facilitating phosphorylated p53 nuclear exclusion and triggering the BAX/caspase-3 apoptotic cascade specifically in senescent endothelial cells