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Among his most significant work is an important study of the use of tumor markers in the evaluation and monitoring of patients with pancreatic cancer

While 5-FU primarily exerts its cytotoxic effects by disrupting DNA synthesis and inducing oxidative stress that exceeds a cytotoxic threshold 27 , cancer cells often counteract this oxidative stress by upregulating antioxidant defenses, leading to therapy resistance 10

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Pfizer secured global rights to YP05002, an oral small-molecule GLP-1 from YaoPharma/Fosun (up to ~$1.9B)