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Some patients report feeling colder than usual whilst taking these medications, although this is not listed as an adverse effect in the Summary of Product Characteristics (SmPCs) for GLP-1 preparations in the UK

Heat puts extra strain on systems already adapting to the drug

These inducers can help individuals transition away from GLP-1 medications while maintaining effective weight and glucose level management

doi: 10.1016/j.bbr.2018.08.006 Summary Keywords Alzheimers disease, GLP-1R agonists, cognitive function, amyloid beta, tau phosphorylation Citation Du H, Meng X, Yao Y and Xu J (2022) The mechanism and efficacy of GLP-1 receptor agonists in the treatment of Alzheimers disease