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J Biomed Opt 9, 11981205 (2004)

Failing heart-relevant processes included increased uptake of long-chain fatty acids, impaired ATP production, cytosolic accumulation of deleterious lipid intermediates, impaired mitochondrial function, suppression of nutrient-deprivation signaling, cytosolic accumulation of amino acids driving aberrant mTOR activation, and inflammation-mediated functional iron deficiency with altered metabolism

It generates a foam thrust, ensuring uniform drug distribution throughout the rectum and significantly enhancing dual-hormone drug absorption, marking a breakthrough in diabetes treatment

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