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Systemic Inflammation Level of Evidence: Limited evidence While ALCs effects on neuroinflammation are well-documented, evidence for systemic anti-inflammatory effects is more limited

Metabolism 63:11781187

However, gastrointestinal symptoms like nausea and gastric discomfort are reported in 20-40% of patients, depending on dose and medication type

The authors also address ongoing challenges of accessibility and affordability, prompting important societal discussions about equitable distribution and funding for these lifechanging therapies