tirzepatide and mdma attenuates mesolimbic cocaine-evoked dopamine levels reduces cocaine taking, motivation and seeking behaviours in male rodents FDA Designates MDMA As 'Breakthrough

These observations prompted new clinical studies designed specifically to measure GLP-1's effect on weight loss rather than glucose control

Ozempic lawsuits allege Novo Nordisk failed to adequately warn patients and healthcare providers about serious gastrointestinal risks including gastroparesis, pancreatitis, bowel obstruction, and vision loss (NAION)

It is available in pill or powder form

And the addressable population is about to expand significantly further, because the FDA approved the first oral GLP-1 formulation at the end of 2025, removing the barrier of weekly injections that has kept many potential users from starting treatment