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Semaglutide and liraglutide exhibited higher rates of decreased appetite in our analysis, primarily driven by central nervous system-mediated satiety regulation, delayed gastric emptying, and modulation of appetite-regulating hormones such as ghrelin (Gupta and Sharma, 2025

Review cadence: early follow-ups to assess tolerability, then ongoing reviews focused on HbA1c, weight trajectory, cardiometabolic markers and overall wellbeing

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