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Those with objective evidence of disease control (normal fecal calprotectin, endoscopic remission) may be better candidates than those with frequent flares or active inflammation

Make a plan before your last dose Rutledge recommends using your time on a GLP-1 medication intentionally: Develop non-food ways to cope with stress, focus on improving the quality of your diet rather than simply eating less and expect hunger to return not as a sign you've failed, but as a normal biological response

"Beyond the obvious body composition perspective, what actually matters is reducing the risk of obesity-related disease and complications, as we prioritized in our 2025 AACE Clinical Practice Algorithm," he says

Both medications are intended as long-term, chronic treatments rather than short-term interventions