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Rhythm disturbances have also been reported in all lcFAODs except CPT1A deficiency, and can occur with, but also without, the presence of cardiomyopathy [20, 31]

In this 2002 seminal veterinary journal article on the use of the LA/Ao in detecting left atrial enlargement -- Left atrial to aortic root indices using two-dimensional and m-mode echocardiography in cavalier king charles spaniels with and without left atrial enlargement -- authors Kerstin Hansson, Jens Haggstrom, Clarence Kvart, and Peter Lord warned against blindly relying upon the LA/Ao as the ultimate determinant of LA enlargement

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J Ped Neurol 2012