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Health systems like VCU Health and Valley Health have developed dedicated weight management programs that incorporate medical treatments, including GLP-1 medications like Mounjaro, along with nutrition counseling and behavioral support

Similarly, in the recent OASIS-1 study, 76% of participants with prediabetes achieved normalization of blood glucose after 68 weeks of treatment with oral semaglutide 50 mg once a day, compared to 10% of subjects with prediabetes in the placebo group [54]

These medications have reshaped how clinicians think about metabolic health, addressing not only body weight but also fatty liver, insulin resistance, and cardiovascular risk