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However, I do believe that there is a gap in the review in tying molecular processes of GSHR1a dimerization to specific neuroanatomical regions (as alluded to on page 30) as a bridge to normal and pathological behaviors

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A pragmatic response to this situation might be to suggest that for women who are on the pill and very keen to avoid pregnancy, that while they are experiencing active weight loss on GLP-1 [receptor agonists], they might consider themselves to be at higher risk of pregnancy and use additional methods, such as barrier contraception, until their weight stabilises, after which it seems likely that contraceptive efficacy would return towards normal. Hammarberg agreed

Front Neurosci 12:985