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doi: 10.3390/ijms24108643 10 European Medicines Agency (2024)

The study had been triggered by some initial reports of reduced urge in semaglutide users to smoke.The study compared 222 942 new users of antidiabetes medications including 5967 of semaglutide

The peptide is endogenously present in human plasma at low nanomolar concentrations in young adults, with the concentration declining with age (a finding from the original GHK research literature that is frequently cited in discussions of the compound)