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Description

Optimization of tolerability and efficacy of the novel dual amylin and calcitonin receptor agonist KBP-089 through dose escalation and combination with a GLP-1 analog

The assessment of gene expression by qPCR was performed as previously described [27, 28]

August 25, 2016

In mediation analysis, semaglutide was found to have a direct effect on reducing total daily insulin dose by 8.9 U per day to 11.4 U per day, with the largest effect observed at the start of treatment