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Each Wegovy pen contains 4 doses and will therefore last 4 weeks

In other words, because GLP-1 medication contains such high doses of the hormone, it may also have an effect in the joints, where levels are otherwise low

Nayak L, Sweet DR, Thomas A, Lapping SD, Kalikasingh K, Madera A, Vinayachandran V, Padmanabhan R, Vasudevan NT, Myers JT, Huang AY, Schmaier A, Mackman N, Liao X, Maiseyeu A, Jain MK (2022) A targetable pathway in neutrophils mitigates both arterial and venous thrombosis

The VA-IMPACT trial is attempting fill this gap by evaluating cardiovascular outcomes in patients with pre-diabetes and established CVD treated with metformin versus placebo (NCT02915198)