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Do not increase your dose ahead of schedule just because the starting dose feels inactive

FDA prescribing information warns that gastrointestinal reactions can lead to dehydration and volume depletion

Danese S, Semeraro S, Marini M, et al

Moreover, HA functions as an active targeting moiety to recognize the transmembrane glycoprotein CD44 receptor, which is overexpressed on surfaces of various tumor cells ( Modification with biomacromolecules Biomacromolecules, such as proteins, DNA, and peptides, have attracted so much attention in drug delivery because of their rich functions, biocompatibility, and stability in the body environment