Total weight loss at 48-68 weeks on the combination is difficult to predict without clinical trial data, but based on individual compound data (retatrutide at 24-28.7% and the additive benefit seen with CagriSema), a reasonable estimate for the combination is 25-35% total body weight reduction in high responders
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By binding G-actin, thymosin beta-4 helps regulate the available pool of monomeric actin that cells draw on for cytoskeletal remodeling, which is part of how cells migrate during wound repair
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