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The primary legal theory involves failure to warn claims under both strict liability and negligence doctrines

Summary of clinical trials of A2AR antagonists for PD with symptom improvements A 2A R: adenosine A 2A receptor, BID: twice a day, L-DOPA: levodopa, PD: Parkinsons disease

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Other documented adverse effects include injection site reactions, fatigue, hypoglycemia (particularly when used with insulin or insulin secretagogues), and increased heart rate