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The protective effects of GLP-1 RAs against cardiovascular events have been demonstrated in several studies, thus supporting their application in patients with heart failure with preserved ejection fraction and DM2 ( Taken together, GLP-1 is a major metabolic and regulatory hormone, with many potential therapeutic implications beyond glycemic control, encompassing cardiovascular protection, enhanced renal function, and the potential benefits in hepatic disease

There was no significant reported difference in the eGFR decline from baseline to the end of treatment or in the rate of renal death ( 2 ) was safe and effective (Mosenzon et al., 2019a)

Published qualitative research from the phase 2 trial found that 31 out of 36 retatrutide-treated participants reported meaningful changes in eating behaviors within the first eight weeks of treatment

In the meantime, keep taking your medication as prescribed