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The other consistent context in the preclinical literature is a metabolic environment the mouse studies pair the compound with diet/energy-balance conditions rather than testing it in isolation

By isolating this fragment, Metabolic Pharmaceuticals hypothesized they could create a "lean" growth hormone analogone capable of promoting fat loss without the anabolic or metabolic complications of full GH replacement therapy

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2007, PMID 17703734) tested AHK-Cu on isolated human hair follicles and dermal papilla cells in culture at picomolar-to-nanomolar concentrations not as a topical product on people