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LudvikBGiorginoFJDAREFriasJPFernndez LandLBrownKet al

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Women with a family history of PCOS or type 2 diabetes are at a higher risk of developing the condition

Similar content being viewed by others Introduction Deregulation of two major signalling pathways, the RAS-RAF-MEK-ERK and PI3K-AKT-PTEN, are key drivers of melanoma development and progression [1], with ~50% and ~25% of patients expressing constitutively active mutants of MAP-kinases BRAF and NRAS, respectively [2]