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When studied together, the results suggest a pincer maneuver approach: The GLP-1 helps manage the input by controlling appetite and caloric intake
H 2 O 2 enhances the spontaneous phasic contractions of isolated human-bladder strips via activation of TRPA1 channels on sensory nerves and the release of substance P and PGE2
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The growing success of GLP-1 receptor agonists has opened the door to peptide-based therapies for a new group of clinicians, but responsible, evidence-informed practice is what will carry the field forward
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