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Further, GLP-1RAs significantly reduce the risk of MI and stroke, but have a neutral effect on hospitalization for heart failure upon 5 available CVOTs [49]
Published phase 2 obesity trial details for retatrutide: New England Journal of Medicine trial
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SURMOUNT-4 will address the question of weight regain after stopping the drug: patients who took tirzepatide for 6 months, will be assessed for sustained weight loss one year later (NCT04660643)
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