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Avoid repeated freeze-thaw cycles, as this degrades the peptide structure

SGLT2 inhibitors when used as an add-on therapy to metformin, insulin, thiazolidinediones, DPP-4 inhibitors, GLP-1 RAs, sulfonylureas, or metformin DPP-4 inhibitor were similarly effective in reducing A1c levels as when used in monotherapy (22,139)

Albiglutide (GlaxoSmithKline) is a fusion of two GLP-1 molecules with human albumin, which increases the proteolytic stability of GLP-1 and slows renal clearance, extending the half-life to 120 h

The evidence for milk thistle directly preventing liver disease or relieving its symptoms is limited, as more high-quality randomized controlled trials are needed to provide sufficient evidence of its benefits