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Medically reviewed by the Acbadem International Medical Board July 15, 2026 Retatrutide is an investigational medicine being studied mainly for obesity and type 2 diabetes

Weight Loss Results: In a 48-week trial with people who had obesity: 12 mg dose: Average weight loss of 24.2% 8 mg dose: Average weight loss of 17.5% Placebo: Weight loss of 2.1% Let me put that in perspective: If you weigh 250 pounds: 24.2% weight loss = 60 pounds lost And people were still losing weight when the trial ended (no plateau reached yet) How this compares to other medications: Semaglutide (Wegovy): ~15% weight loss Tirzepatide (Zepbound): ~20% weight loss Retatrutide: ~24% weight loss This is the most significant weight loss we've seen with any medication to date

Mild dehydration was messing with my metabolism

This double effect keeps your blood sugar levels in check