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Stopping the semaglutide 3 to 5 days before surgery was identified as an independent risk factor for aspiration pneumonitis, while the 7-day, 14-day, and 30-day cohorts had no independent risk factor for aspiration pneumonitis

According to a clinical study, users taking 1 mg semaglutide experienced a 0.6 % HbA1c reduction from the baseline (8.28%), and fasting blood glucose was 7.8 mmol/L from the baseline (9.6 mmol/L) in the first 4 weeks

Retatrutide has not received FDA approval and is currently only available through clinical trials

To put that in perspective, the best semaglutide clinical trials showed approximately 15-17% weight reduction, and tirzepatide results peaked around 20-22%