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Triglycerides show even greater improvement, with reductions of 15-20 mg/dL per 10-kilogram weight loss

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for several indications: type 2 diabetes management (under the brand names Ozempic and Rybelsus), chronic weight management in adults with obesity (BMI 30) or overweight (BMI 27) with at least one weight-related comorbidity (under the brand name Wegovy), and in adolescents aged 12 years and older with obesity

A phase I/II clinical trial found that the most common side effects were mild and transient (Teichman et al., 2006): Injection site reactions (redness, mild swelling) Headaches Flushing or warmth Temporary water retention Joint tightness or tingling Transient fatigue or dizziness Serious adverse events are rare when the peptide is used under medical supervision at appropriate doses

An intestinal illness caused by a parasite called Cyclospora cayetanensis