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There is something wrong with an intervention that has the exact opposite of the intended effect the majority of the time, she says

Approved by the MHRA Because of the results of the trial, the UKs Medicines and Healthcare products Regulatory Agency (MHRA) has approved Wegovy as a treatment for preventing heart problems in overweight and obese adults with pre-existing cardiovascular disease

Published data suggests that activating all three pathways simultaneously creates a synergistic effect that is meaningfully distinct from mono or dual-receptor activation alone

doi: 10.1038/nrendo.2010.228