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Statement on the Safety of Synthetic L-Ergothioneine as a Novel Food - Supplementary Dietary Exposure and Safety Assessment for Infants and Young Children, Pregnant and Breastfeeding Women

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) small, chemically defined, amenable to standard analytical frameworks Studied for hTERT upregulation in human fibroblast cell culture models published in peer-reviewed literature Research tool for telomerase enzyme activity assays, TRAP assays, and telomere length measurement studies Studied in bovine cumulus cell and cumulus-oocyte complex models for telomerase activity published in PMC Examined for DNA binding interactions with specific ATTTG sequence motifs in structural biology research Referenced in over 100 publications primarily from the St

In the GHK-Cu complex, the copper ion coordinates with the nitrogen atom from the imidazole side chain of histidine, the alpha-amino group nitrogen from glycine, and the deprotonated amide nitrogen of the glycine-histidine peptide bond