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Description

The most commonly reported is mild injection site redness or warmth, which typically resolves within minutes

Start: Begin at 2,667 mcg total (~10 units) once daily to gauge tolerability

The most common experimental dose in animal studies (Sikiric et al.) is 10 g/kg/day intraperitoneally or orally in rats

While extrapolated data from UK/US, CF clinics suggest a prevalence of 1:12,0001:40,000 among Indian children (95), a 2020 North Indian study revealed a high CFTR mutation carrier rate of 1:22, signaling a potentially higher prevalence (96)