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Warnings Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

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fructosamine or glycated albumin may also be considered as short-term alternatives when HbA1c is unreliable Document the timing of B12 treatment initiation in the patient's records to contextualise any HbA1c results obtained during this period This approach ensures that clinical decisions regarding diabetes diagnosis or medication adjustment are based on accurate data rather than a transiently distorted HbA1c result