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In a human study (11 men on warfarin for at least 90 days), no difference in calcium urinary excretion was seen between the patients taking warfarin and the control group, as well as between people taking warfarin and people who had stopped warfarin, suggesting that there is no important role of a vitamin K-dependent mechanism in renal calcium excretion [343]

Eur Respir Rev 2024;33:240001

The appropriate concentrations of DHLA and LA to set distinct redox potentials were calculated from the Nernst equation based on the standard reduction potential of lipoic acid ( E LA ) of 290 mV at pH 7.0 (Lees and Whitesides, The redox potential for each of the two redox pairs is defined by the Nernst equation using the respective midpoint potential and ratios ( Q ) of oxidized to reduced roGFP and LA to DHLA, respectively (Equation 2)

The NMDA-R blocker memantine had some initial encouraging results [116,117,118,119] However, the largest study (N=138, 8 weeks), had negative results [120]