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Nevertheless, it is of inefficiency for dHL-60 to generate NETs compared to neutrophils, and differences including the dynamics pattern of the cytoskeleton, endomembrane, phagocytosis abilities and calcium influx exist between dHL-60 and neutrophils

In 24 hpi trophozoite-stage parasites, hemoglobin and heme levels were not measurably different, but hemozoin levels were significantly decreased in resistant parasites compared to sensitive parasites (Fig 2B), indicative of decreased turnover of heme into hemozoin in resistant parasites over the preceding 24 h of the parasite lifecycle

In contrast, the FAT domain scaffold forms critical interactions with focal adhesion proteins and oncogenic receptor tyrosine kinases, mediating multiple signaling cascades for tumorigenesis, providing a potentially safe and effective therapeutic advantage over traditional kinase inhibition (Supplementary Fig

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