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Risks and uncertainties include, among other things, the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and/or completion dates for clinical trials, regulatory submission dates, regulatory approval dates and/or launch dates, as well as the possibility of unfavorable new clinical data and further analyses of existing clinical data

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This represents an honest scientific debate rather than a settled question

In patients with baseline normal ammonia levels, the NIRS data of l-carnitine group (n = 31) at 8 weeks of treatment were significantly better than that of the control group (n = 25) (0.11 0.09 vs