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As MASLD progresses, hepatic inflammation, particularly involving M1 macrophages (Kupffer cells), becomes a key factor in disease progression (63)

doi: 10.1016/j.freeradbiomed.2011.09.014 126 LiSHeYChenKSunJZhangLHeYet al

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I think its better to be conservative and just maximize the effects of the lower doses before youre increasing, so that you end up with more weight loss overall that way. She even has an opinion on how you should weigh yourself between visits